
Early life and beauty pageants:
Menounos, a Greek American, was born in Medford, Massachusetts, and is fluent in the Greek language. At age 17, she was an employee of Dunkin' Donuts with aspirations to be something more. Menounos attended the Holy Trinity Greek Orthodox Church. In 1995, Menounos began to compete in beauty pageants. The following year, she won the title of Miss Massachusetts Teen USA and competed at Miss Teen USA where she failed to place in the top 10. Menounos did however place in the top 15, receiving an honorary mention, during the preliminary competition; Menounos placed 13th in preliminaries. The pageant was won by Christie Lee Woods. Maria competed for the title of Miss Massachusetts USA 2000; she was the 1st runner up.

Later Menounos attended Boston's Emerson College where she participated in the now award winning organization, Emerson Independent Video. During her senior year, she was hired as a reporter for Channel One News. Her work for Channel One's 10-minute segments included traveling to El Salvador to report on the earthquake of 2001 and interviewing then President George W. Bush.
Entertainment Tonight hired Menounos as a correspondent in 2002, where she reported on movies, music and fashion. ET executives offered her a hosting gig for ET on MTV & VH1; she left the program in 2005 to focus on her acting career, though she would eventually join rival program Access Hollywood later that Fall as a special correspondent. She went on to co-host a few episodes of the Today show in the late summer and fall of 2006 as well as in April 2007.
In 2003, Menounos appeared on the November 30 episode of Punk'd where she was one of many celebrities caught in the awkward and embarrassing "Red Carpet Interviews".
In the summer of 2005, she appeared in the comic book film Fantastic Four, where she played a nurse who is romanced by the "Human Torch", played by Chris Evans. Her likeness and voice was featured in the 2005 Electronic Arts video game, From Russia with Love as Eva Adara, Red Grant's henchwoman, which stars Sean Connery as James Bond. She is also the spokesperson for Pantene hair products.
Menounos presented the 2006 Eurovision Song Contest (along with Greek singer Sakis Rouvas) that took place in Athens.

Menounos also appeared on the Scrubs episode "My Extra Mile", which aired in May 2006 where she is attracted to John Dorian because she likes his hair.
In 2006, Menounos appeared in the music video for "A Public Affair" by Jessica Simpson. In April 27, 2007, Maria starred in Kickin' It Old Skool. In 2007, Menounos continued in her run as international spokesperson doing print and television commercials for Pantene hair products as well as print ads for New York & Company.
From December 17 to December 20, 2007, Menounos hosted the reality game show miniseries Clash of the Choirs.
In 2008, she became the host of "Hollywood Green" on the "Planet Green" network. "Maria Menounos brings glamour to green living as the hostess of Hollywood Green. Both as the special correspondent for daily entertainment newsmagazine "Access Hollywood," and on Hollywood Green, Maria provides TV viewers with comprehensive coverage of entertainment and news personalities."
In 2008, she had a role in the movie Tropic Thunder.
In 2008, she became the first journalist to interview the entire Obama family as a whole. She is represented by Creative Artists Agency.

In November 2008, when Richard Belzer fell ill, she filled in as host for the North Shore Animal League’s Dogcatemy Celebrity Gala, which takes place at NYC’s Capitale.
In 2009, she hosted reunion specials of MTV's The Real World: Brooklyn, the Real World/Road Rules Challenge: The Duel 2, The Real World: Cancun and the Real World/Road Rules Challenge: The Ruins.
Menounos appeared on the Knight Rider 2008 series episode "Fly By Knight", which aired on February 11, 2009 where she played a DEA agent who is in charge of investigating a plane crash.
On October 12 Menounos joined Nancy O'Dell when O'Dell guest hosted WWE Raw. She was involved in a six diva tag team match with Kelly Kelly and Gail Kim against Beth Phoenix, Rosa Mendes, and Alicia Fox. Menounos's team came out with the victory when Kelly Kelly pinned Rosa.

At the age of 17, Menounos produced In the Land of Merry Misfits, an independent film fairy tale. The 35 mm feature film was produced by Menounos while attending Emerson College with director Keven Undergaro, then head writer for MTV's Singled Out. The negative of the film was stolen and the film was never completed but her work on the film, and the film's director, helped her land her reporting job at Channel One News and at MTV (ET on MTV). Menounos, however, never forgot the film or the film's director. In 2005, Menounos personally funded the recovery and restoration of the film, which was narrated by John Waters and starred an eclectic group in the Waters vein — including former WWE champion Bob Backlund, actress Josie Davis from the TV show "Charles in Charge" and B-movie icon Randal Malone. The film premiered at the 2007 Tribeca Film Festival.
Menounos also directed Longtime Listener starring Wilmer Valderrama. The film was an official selection of the Tribeca Film Festival 2006.

Menounos appeared in FHM magazine and in People magazine in 2004 as one of the "50 Most Beautiful People." In another poll conducted by askmen.com, Menounos was voted one of the top five girls a guy would most want to marry, along with Angelina Jolie, Charlize Theron and Jessica Alba. She has also beaten Jessica Alba and Charlize Theron for "Cyber Vixen of the Year" on Spike TV's video game awards.
Charity work:
Menounos founded the charity "Take Action Hollywood!" after her trip to South Africa. Reporting on the devastating effects of the AIDS crisis she was inspired to create TAH!, a charity that utilizes the power of the entertainment industry and the medium of film to affect for positive social change. Maria also created the Cosmo Girl Cup, a national, annual competition and award given to the group of teens who do the most in their communities to affect for positive social change.